Main trade-off
ASUSTOR Nimbustor 4 Gen2
The extra hardware does not bring Synology's DSM applications.
Head-to-head
Choose AS5404T for four NVMe positions, more official RAM headroom and two 2.5GbE ports. Choose DS425+ if DSM photos and backup tools fit the way you manage files. Both hold four SATA drives, so the difference is the surrounding hardware and software, rather than basic hard-drive capacity.
Before you choose
Four compatible 12 TB hard drives in RAID 5 provide 36 TB before overhead on either model. Choosing ASUSTOR does not create extra hard-drive capacity, and choosing Synology does not reduce it for this equal-drive example.
What this is based on
(4 - 1) × 12 TB = 36 TB before formatting and system overhead. Both models have four SATA bays and support RAID 5.
Main trade-off
The extra hardware does not bring Synology's DSM applications.
Main trade-off
Two NVMe slots and 6 GB official RAM maximum.


ASUSTOR AS5404T vs Synology DS425+ for a four-drive NAS. Compare NVMe layouts, memory headroom, network ports and the real cost of the SSD plan.
Choose AS5404T for four NVMe positions, more official RAM headroom and two 2.5GbE ports. Choose DS425+ if DSM photos and backup tools fit the way you manage files. Both hold four SATA drives, so the difference is the surrounding hardware and software, rather than basic hard-drive capacity.
Winner by situation
Both support the same basic four-drive layout.
ASUSTOR provides four slots and Synology provides two.
ASUSTOR supports up to 16 GB. Synology's official ceiling is 6 GB.
DS425+ provides DSM and its associated packages. Check each package requirement.
What matters in practice
Four compatible 12 TB hard drives in RAID 5 provide 36 TB before overhead on either model. Choosing ASUSTOR does not create extra hard-drive capacity, and choosing Synology does not reduce it for this equal-drive example.
(4 - 1) × 12 TB = 36 TB before formatting and system overhead. Both models have four SATA bays and support RAID 5.
A plan with one two-SSD mirror for applications and another two-SSD mirror for a separate workload needs four NVMe slots. AS5404T has the physical positions. DS425+ has only two, so it cannot build that exact all-NVMe layout internally.
2 drives in the first mirror + 2 drives in the second = 4 NVMe positions. AS5404T has 4 and DS425+ has 2. Software and compatible drives still need checking.
AS5404T is 25 mm narrower than DS425+ but 7 mm deeper. A tight side-by-side shelf may favor ASUSTOR, while a shallow cabinet may favor Synology. Neither dimension comparison includes cable and ventilation clearance.
199 - 174 = 25 mm width difference. 230 - 223 = 7 mm depth difference.

ASUSTOR, AS5404T
The chassis has 4-bay storage. Its fastest documented network path is 2.5 Gbps.

Synology, DS425+
The chassis has 4-bay storage. Its fastest documented network path is 2.5 Gbps.
Meaningful differences
| What changes | ASUSTOR Nimbustor 4 Gen2 | Synology DiskStation DS425+ | Why it matters |
|---|---|---|---|
| SATA drive positions | 4 | 4 | The same equal-drive RAID layout has the same nominal capacity arithmetic. |
| M.2 NVMe slots | 4 | 2 | ASUSTOR has two more physical NVMe positions. |
| Installed / maximum memory | 4 GB / 16 GB | 2 GB / 6 GB | Compare the requirements of the actual apps, not just the maximum number. |
| Ethernet ports | Two 2.5GbE | One 2.5GbE and one 1GbE | Each supports one 2.5GbE link. Additional links require a suitable network configuration. |
| NVMe storage planning | Compatible NVMe storage or caching | Storage pools require Synology-verified SSDs | The physical slot does not establish support for any SSD you already own. |
| Case width and depth | 174 × 230 mm | 199 × 223 mm | ASUSTOR is narrower, while Synology is slightly shallower. |
What you give up
Recommendation switch
Choose ASUSTOR Nimbustor 4 Gen2. Only AS5404T has four M.2 slots.
Choose Synology DiskStation DS425+. DS425+ provides the Synology workflow with four SATA bays.
What matters in practice
Four hard-drive bays cover the same basic storage layouts on both models. The extra ASUSTOR NVMe slots and memory support matter when a specific workload needs them. If you mainly want DSM's photo organization and backup routine, unused hardware capacity elsewhere may be less important than that daily workflow.
Synology's current specifications allow M.2 storage pools, with a requirement for Synology-verified SSDs. It would be wrong to describe those slots as cache-only, or to assume any spare NVMe drive is supported. Check the exact drive and firmware before building the budget around an SSD already in a drawer.
ASUSTOR has two 2.5GbE ports, while Synology mixes 2.5GbE and 1GbE. Both can connect a suitable client through one 2.5GbE path. Using multiple links effectively depends on the protocol, client and network setup. Do not add the port labels together and treat the result as a guaranteed copy speed.
What the facts say
Useful conclusions from the current NAS devices comparison, followed by the checked facts used to reach them.
| Product | Needs matched | Checked facts | Source records |
|---|---|---|---|
| ASUSTOR Nimbustor 4 Gen2 |
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| Synology DiskStation DS425+ |
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Ready to choose?
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Keep four hard drives and plan several NVMe devices
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Use DSM for photos, shared files and backups
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